Almighty Allah first created the Noor of the Holy Prophet Muhammad (sallal laahu alaihi wasallam) from His Noor.
The first adult free male to accept Islam was Hazrat Abu Bakr Siddique (radi Allahu anhu); the first woman was Hazrat Khadija (radi Allahu anha); amongst the children, Hazrat Ali (radi Allahu anhu); among the freed slaves, Hazrat Zaid Bin Haarith (radi Allahu anhu); and amongst the slaves was Hazrat Bilal (radi Allahu anhu).
The first wife of the Holy Prophet Muhammad (sallal laahu alaihi wasallam) was Hazrat Khadijatul Kubra (radi Allahu anha).
Hazrat Khadija (radi Allahu anha) was the first of the Holy Prophet's (sallal laahu alaihi wasallam) wives to pass away.
Hazrat Qaasim (radi Allahu anhu) was the first of the Holy Prophet's (sallal laahu alaihi wasallam) children to be born. He passed away in his infancy.
Hazrat Khadija (radi Allahu anha) was the first person to read Namaaz amongst the Ummah of the Prophet (sallal laahu alaihi wasallam).
The home of Hazrat Abu Ayub Ansaari (radi Allahu anhu) was the first place where the Prophet (sallal laahu alaihi wasallam) stayed in Madina Shareef.
The first verse of the Holy Quran to be revealed was �Iqra Bi Ismi Rabbikal Lazi Khalaq�. This took place on Friday, 27th of Ramadaan on the night of Qadr thirteen and a half years before Hijra, coinciding with the 14th of August 610 A.C. in the cave of Hira.
Hazrat Jibraeel (alaihis salaam) gave the first Azaan in the skies.
The first Azaan on earth was given by Hazrat Adam (alaihis salaam).
Hazrat Bilal (radi Allahu anhu) gave the first Azaan in the year 1 A.H. to announce the Namaaz of Fajr.
The Prophet (sallal laahu alaihi wasallam) performed the first Jummah Salaah in Madina Munawwarah on the 12th of Rabi-ul-Awwal.
The first Hajj became Fardh in the year 9 A.H.
The first Fardh fast was that of Ashurah (10th Muharram). This was then nullified and the fasting on the 13th, 14th and 15th of every lunar month became Fardh. This was also nullified, and on the 10th of Shawaal in 2 A.H., fasting for the entire month of Ramadaan was made Fardh and the remainder of the fasts was made Nafil (optional).
The first Muslims migrated towards Abyssinia.
The first battle to take place was the Ghazwa Abwaa.
The first Sadqa was given by Hazrat Adi bin Haatim (radi Allahu anhu) on behalf of his people.
The Holy Prophet (sallal laahu alaihi wasallam) established the first madrassah (Suffah) in Musjid-e-Nabawi.
The first person sent to spread Islam under the instructions of the Holy Prophet (sallal laahu alaihi wasallam) was Hazrat Mus'ab bin Umair (radi Allahu anhu), who was sent to Madinah.
The first person to be appointed a teacher in the madrassah was Hazrat Mus'ab bin Umair (radi Allahu anhu).
The first Mosque to be built was Musjid-e-Quba, which the Prophet (sallal laahu alaihi wasallam) built himself. After the Holy Kaaba, the Musjid-e-Nabawi and the Musjid-e-Aqsa, the most excellence is given to Musjid-e-Quba. Two rakaats of Salaah in this Musjid is equivalent to the Sawaab of one Umrah.
Sayyiduna Ameer Mu�awiyah (radi Allahu anhu) constructed the first Minaret built for the purpose of Azaan.
The first Mehraab for Imaamat was built by Sayyiduna Umar bin Abdul Aziz (radi Allahu anhu).
Hazrat Tameem Daari (radi Allahu anhu) was the first person who sent his slave, Fateh, to light a candle in Musjid-e-Nabawi. Due to this act, the Holy Prophet (sallal laahu alaihi wasallam) changed his name to �Siraaj�.
The first Shaheed (Martyr) was Sayyiduna Amaar bin Yaasir (radi Allahu anhu).